Early Pro-inflammatory Microglia Activation After Inflammation-Sensitized Hypoxic-Ischemic Brain Injury in Neonatal Rats

Early Pro-inflammatory Microglia Activation After Inflammation-Sensitized Hypoxic-Ischemic Brain Injury in Neonatal Rats

Background: Perinatal asphyxia, leading to neonatal encephalopathy, is one of the leading causes for child mortality and long-term morbidities. Neonatal encephalopathy rates are significantly increased in newborns with perinatal infection. Therapeutic hypothermia is only neuroprotective in 50% of co...

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Bibliographic Details
Main Authors: Meray Serdar, Karina Kempe, Mandana Rizazad, Josephine Herz, Ivo Bendix, Ursula Felderhoff-Müser, Hemmen Sabir
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
newborn
HIE
brain
infection
inflammation
microglia
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00237/full

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https://www.frontiersin.org/article/10.3389/fncel.2019.00237/full

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