Xijiao Dihuang Decoction combined with Yinqiao Powder reverses influenza virus-induced F-actin reorganization in PMVECs by inhibiting ERM phosphorylation

Xijiao Dihuang Decoction combined with Yinqiao Powder reverses influenza virus-induced F-actin reorganization in PMVECs by inhibiting ERM phosphorylation

Objective: It has been documented that ezrin/radixin/moesin (ERM) phosphorylation by the p38 mitogen-activated protein kinase (MAPK), Rho/ROCK, and protein kinase C (PKC) pathways leads to filamentous actin (F-actin) reorganization and microvascular endothelial cell hyperpermeability. In this study,...

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Bibliographic Details
Main Authors: Zinan Xuan, Ying Wu, Chenyue Zhang, Shujing Zhang, Xiangyang Chen, Shuyu Li, Yu Hao, Qian Wang, Xudan Wang, Shu Zhang
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Journal of Traditional Chinese Medical Sciences
Subjects:
Xijiao Dihuang Decoction combined with Yinqiao Powder
Influenza virus
Pulmonary microvascular endothelial cells
Filamentous actin
Ezrin/radixin/moesin
Online Access:http://www.sciencedirect.com/science/article/pii/S209575481630062X

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http://www.sciencedirect.com/science/article/pii/S209575481630062X

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