MALDI-TOF peptidomic analysis of serum and post-prostatic massage urine specimens to identify prostate cancer biomarkers

MALDI-TOF peptidomic analysis of serum and post-prostatic massage urine specimens to identify prostate cancer biomarkers

Abstract Background Lower urinary tract symptoms (LUTS) and prostate specific antigen-based parameters seem to have only a limited utility for the differential diagnosis of prostate cancer (PCa). MALDI-TOF/MS peptidomic profiling could be a useful diagnostic tool for biomarker discovery, although re...

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Bibliographic Details
Main Authors: Andrea Padoan, Daniela Basso, Carlo-Federico Zambon, Tommaso Prayer-Galetti, Giorgio Arrigoni, Dania Bozzato, Stefania Moz, Filiberto Zattoni, Rino Bellocco, Mario Plebani
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Clinical Proteomics
Subjects:
Prostate cancer
Biomarkers
MALDI-TOF/MS
Data normalization
Measurement error
Regression calibration
Online Access:http://link.springer.com/article/10.1186/s12014-018-9199-8

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http://link.springer.com/article/10.1186/s12014-018-9199-8

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