Reverse pharmacology for developing an anti-malarial phytomedicine. The example of Argemone mexicana

Classical pharmacology has been the basis for the discovery of new chemical entities with therapeutic effects for decades. In natural product research, compounds are generally tested in vivo only after full in vitro characterization. However drug screening using this methodology is expensive, time-...

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Bibliographic Details
Main Authors: Claudia Simoes-Pires, Kurt Hostettmann, Amina Haouala, Muriel Cuendet, Jacques Falquet, Bertrand Graz, Philippe Christen
Format: Article
Language:English
Published: Elsevier 2014-12-01
Series:International Journal for Parasitology: Drugs and Drug Resistance
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211320714000141