Selenium Inhibits Homocysteine-Induced Endothelial Dysfunction and Apoptosis via Activation of AKT

Background/Aims: Endothelial cells are crucial in vascular homeostasis. Dysfunction of endothelial cells is involved in the development of cardiovascular diseases (CVD). High plasma homocysteine (Hcy) correlates with CVD while selenium supplementation counteracts development of CVD. However, the und...

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Bibliographic Details
Main Authors: Hui Ren, Jianjun Mu, Jingjing Ma, Jie Gong, Jing Li, Jiawen Wang, Tianlin Gao, Peng Zhu, Shikang Zheng, Jing Xie, Bo Yuan
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-02-01
Series:Cellular Physiology and Biochemistry
Subjects:
Online Access:http://www.karger.com/Article/FullText/443041