Paralogs hnRNP L and hnRNP LL exhibit overlapping but distinct RNA binding constraints.

HnRNP (heterogeneous nuclear ribonucleoprotein) proteins are a large family of RNA-binding proteins that regulate numerous aspects of RNA processing. Interestingly, several paralogous pairs of hnRNPs exist that exhibit similar RNA-binding specificity to one another, yet have non-redundant functional...

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Bibliographic Details
Main Authors: Sarah A Smith, Debashish Ray, Kate B Cook, Michael J Mallory, Timothy R Hughes, Kristen W Lynch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3823766?pdf=render