Transcriptomic Changes of Murine Visceral Fat Exposed to Intermittent Hypoxia at Single Cell Resolution

Transcriptomic Changes of Murine Visceral Fat Exposed to Intermittent Hypoxia at Single Cell Resolution

Intermittent hypoxia (IH) is a hallmark of obstructive sleep apnea (OSA) and induces metabolic dysfunction manifesting as inflammation, increased lipolysis and insulin resistance in visceral white adipose tissues (vWAT). However, the cell types and their corresponding transcriptional pathways underl...

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Bibliographic Details
Main Authors: Abdelnaby Khalyfa, Wesley Warren, Jorge Andrade, Christopher A. Bottoms, Edward S. Rice, Rene Cortese, Leila Kheirandish-Gozal, David Gozal
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
intermittent hypoxia
sleep apnea
OSA
single cell
snRNA-seq
bulk RNA-seq
Online Access:https://www.mdpi.com/1422-0067/22/1/261

Internet

https://www.mdpi.com/1422-0067/22/1/261

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