A polymorphism in the HLA-DPB1 gene is associated with susceptibility to multiple sclerosis.

A polymorphism in the HLA-DPB1 gene is associated with susceptibility to multiple sclerosis.

We conducted an association study across the human leukocyte antigen (HLA) complex to identify loci associated with multiple sclerosis (MS). Comparing 1927 SNPs in 1618 MS cases and 3413 controls of European ancestry, we identified seven SNPs that were independently associated with MS conditional on...

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Bibliographic Details
Main Authors: Judith Field, Sharon R Browning, Laura J Johnson, Patrick Danoy, Michael D Varney, Brian D Tait, Kaushal S Gandhi, Jac C Charlesworth, Robert N Heard, Australia and New Zealand Multiple Sclerosis Genetics Consortium, Graeme J Stewart, Trevor J Kilpatrick, Simon J Foote, Melanie Bahlo, Helmut Butzkueven, James Wiley, David R Booth, Bruce V Taylor, Matthew A Brown, Justin P Rubio, Jim Stankovich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2964313?pdf=render

Internet

http://europepmc.org/articles/PMC2964313?pdf=render

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