Anti-leishmanial activity of alkaloidal extract from Aspidosperma ramiflorum

Infections due to protozoa of the genus Leishmania are a major worldwide health problem, with high endemicity in developing countries. The drugs of choice for the treatment of leishmaniasis are the pentavalent antimonials (SbV), which present renal and cardiac toxicity. Besides, the precise chemical...

Full description

Bibliographic Details
Main Authors: Izabel Cristina Piloto Ferreira, Maria Valdrinez Campana Lonardoni, Gerzia MC Machado, Leonor L Leon, Lucílio Gobbi Filho, Luís Henrique Bissoli Pinto, Arildo José Braz de Oliveira
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2004-05-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762004000300015