Staphylococcus aureus induces COX-2-dependent proliferation and malignant transformation in oral keratinocytes

Staphylococcus aureus induces COX-2-dependent proliferation and malignant transformation in oral keratinocytes

The COX-2/PGE2 axis can play roles in mediating the progression of tumor. COX-2 induction was observed in oral cancer. In our previous study, we found Staphylococcus aureus, a pathogen prevalent in oral cancer, can activate the COX-2/PGE2 pathway in human oral keratinocyte (HOK) cells. Here, we inve...

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Bibliographic Details
Main Authors: Yuxia Wang, Shiyu Liu, Bolei Li, Yaling Jiang, Xinxuan Zhou, Jing Chen, Mingyun Li, Biao Ren, Xian Peng, Xuedong Zhou, Lei Cheng
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Journal of Oral Microbiology
Subjects:
cox-2
staphylococcus aureus
oral keratinocytes
proliferation
malignant transformation
Online Access:http://dx.doi.org/10.1080/20002297.2019.1643205

Internet

http://dx.doi.org/10.1080/20002297.2019.1643205

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