Mechanisms of induction and maintenance of spike-timing dependent plasticity in biophysical synapse models

We review biophysical models of synaptic plasticity, with a focus on spike-timing dependent plasticity (STDP). The common property of the discussed models is that synaptic changes depend on the dynamics of the intracellular calcium concentration, which itself depends on pre- and postsynaptic act...

Full description

Bibliographic Details
Main Authors: Michael Graupner, Nicolas Brunel
Format: Article
Language:English
Published: Frontiers Media S.A. 2010-09-01
Series:Frontiers in Computational Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncom.2010.00136/full