Development and in vitro evaluation of sustained release multiparticulate tablet of freely water soluble drug

Development and in vitro evaluation of sustained release multiparticulate tablet of freely water soluble drug

Blends of aqueous dispersion of a hydrophobic and hydrophilic polymer, namely Surelease®: hydroxypropyl methylcellulose (Surelease®: HPMC E15) were used as coating materials to control the drug release from coated pellets of the highly water soluble drug metoprolol succinate. Varying the polymer ble...

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Bibliographic Details
Main Authors: Ashlesha Pravin Pandit, Rajendra Dattatray Shinde
Format: Article
Language:English
Published: Universidade de São Paulo 2010-09-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Péletes
Nonpareil
Surelease®
HPMC E15
Revestimento
Técnica da solução em camada
Agente de cushning
Succinato de metoprolol
Pellets
Nonpareil seeds
Coating
Solution layering technique
Cushning agent
Metoprolol succinate
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000300009

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000300009

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