An Intrinsic Transcriptional Program Underlying Synaptic Scaling during Activity Suppression

An Intrinsic Transcriptional Program Underlying Synaptic Scaling during Activity Suppression

Homeostatic scaling allows neurons to maintain stable activity patterns by globally altering their synaptic strength in response to changing activity levels. Suppression of activity by the blocking of action potentials increases synaptic strength through an upregulation of surface α-amino-3-hydroxy-...

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Bibliographic Details
Main Authors: Katie Schaukowitch, Austin L. Reese, Seung-Kyoon Kim, Gokhul Kilaru, Jae-Yeol Joo, Ege T. Kavalali, Tae-Kyung Kim
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:Cell Reports
Subjects:
homeostatic scaling
transcription
Nptx1
T-VGCC
enhancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717300700

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http://www.sciencedirect.com/science/article/pii/S2211124717300700

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