Stromal Activation Associated with Development of Prostate Cancer in Prostate-Targeted Fibroblast Growth Factor 8b Transgenic Mice

Expression of fibroblast growth factor 8 (FGF-8) is commonly increased in prostate cancer. Experimental studies have provided evidence that it plays a role in prostate tumorigenesis and tumor progression. To study how increased FGF-8 affects the prostate, we generated and analyzed transgenic (TG) m...

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Bibliographic Details
Main Authors: Teresa D. Elo, Eeva M. Valve, Jani A. Seppänen, Heikki J. Vuorikoski, Sari I. Mäkelä, Matti Poutanen, Paula M. Kujala, Pirkko L. Härkönen
Format: Article
Language:English
Published: Elsevier 2010-11-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558610800405