The polarity protein Scribble regulates myelination and remyelination in the central nervous system.

The development and regeneration of myelin by oligodendrocytes, the myelin-forming cells of the central nervous system (CNS), requires profound changes in cell shape that lead to myelin sheath initiation and formation. Here, we demonstrate a requirement for the basal polarity complex protein Scribbl...

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Bibliographic Details
Main Authors: Andrew A Jarjour, Amanda Boyd, Lukas E Dow, Rebecca K Holloway, Sandra Goebbels, Patrick O Humbert, Anna Williams, Charles ffrench-Constant
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-03-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.1002107