Skin dendritic cells in melanoma are key for successful checkpoint blockade therapy

Skin dendritic cells in melanoma are key for successful checkpoint blockade therapy

Background Immunotherapy with checkpoint inhibitors has shown impressive results in patients with melanoma, but still many do not benefit from this line of treatment. A lack of tumor-infiltrating T cells is a common reason for therapy failure but also a loss of intratumoral dendritic cells (DCs) has...

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Bibliographic Details
Main Authors: Anastasia Prokopi, Christoph H Tripp, Bart Tummers, Florian Hornsteiner, Sarah Spoeck, Jeremy Chase Crawford, Derek R Clements, Mirjana Efremova, Katharina Hutter, Lydia Bellmann, Giuseppe Cappellano, Bruno L Cadilha, Daniela Ortner, Zlatko Trajanoski, Suzie Chen, Juliana Idoyaga, Douglas R Green, Patrizia Stoitzner
Format: Article
Language:English
Published: BMJ Publishing Group 2021-01-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/9/1/e000832.full

Internet

https://jitc.bmj.com/content/9/1/e000832.full

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