Early Transcriptome Signatures from Immunized Mouse Dendritic Cells Predict Late Vaccine-Induced T-Cell Responses.

Early Transcriptome Signatures from Immunized Mouse Dendritic Cells Predict Late Vaccine-Induced T-Cell Responses.

Systems biology offers promising approaches for identifying response-specific signatures to vaccination and assessing their predictive value. Here, we designed a modelling strategy aiming to predict the quality of late T-cell responses after vaccination from early transcriptome analysis of dendritic...

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Bibliographic Details
Main Authors: Nicolas Dérian, Bertrand Bellier, Hang Phuong Pham, Eliza Tsitoura, Dorothea Kazazi, Christophe Huret, Penelope Mavromara, David Klatzmann, Adrien Six
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-03-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4801398?pdf=render

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http://europepmc.org/articles/PMC4801398?pdf=render

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