Early structural and functional plasticity alterations in a susceptibility period of DYT1 dystonia mouse striatum

Early structural and functional plasticity alterations in a susceptibility period of DYT1 dystonia mouse striatum

The onset of abnormal movements in DYT1 dystonia is between childhood and adolescence, although it is unclear why clinical manifestations appear during this developmental period. Plasticity at corticostriatal synapses is critically involved in motor memory. In the Tor1a+/Δgag DYT1 dystonia mouse mod...

Full description

Bibliographic Details
Main Authors: Marta Maltese, Jennifer Stanic, Annalisa Tassone, Giuseppe Sciamanna, Giulia Ponterio, Valentina Vanni, Giuseppina Martella, Paola Imbriani, Paola Bonsi, Nicola Biagio Mercuri, Fabrizio Gardoni, Antonio Pisani
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-03-01
Series:eLife
Subjects:
synaptic plasticity
dystonia DYT1
BDNF
AMPA receptors
Online Access:https://elifesciences.org/articles/33331

Internet

https://elifesciences.org/articles/33331

Similar Items