Establishment of urinary exosome-like vesicles isolation protocol for FHHNC patients and evaluation of different exosomal RNA extraction methods

Establishment of urinary exosome-like vesicles isolation protocol for FHHNC patients and evaluation of different exosomal RNA extraction methods

Abstract Background Molecular and cellular pathophysiological events occurring in the majority of rare kidney diseases remain to be elucidated. Familial hypomagnesemia with hypercalciuria and nephrocalcinosis (FHHNC) is a rare autosomal recessive disorder caused by mutations in either CLDN16 or CLDN...

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Bibliographic Details
Main Authors: M. Vall-Palomar, J. Arévalo, G. Ariceta, A. Meseguer
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Journal of Translational Medicine
Subjects:
Urinary exosome-like vesicles
Exosome isolation
Exosomal miRNA
FHHNC
Online Access:http://link.springer.com/article/10.1186/s12967-018-1651-z

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http://link.springer.com/article/10.1186/s12967-018-1651-z

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