Defining the recognition elements of Lewis Y-reactive antibodies.

Antibody response to carbohydrate antigens is often independent of T cells and the process of affinity/specificity improvement is considered strictly dependent on the germinal centers. Antibodies induced during a T cell-independent type 2 (TI-2) response are less variable and less functionally versa...

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Bibliographic Details
Main Authors: Somdutta Saha, Anastas Pashov, Eric R Siegel, Ramachandran Murali, Thomas Kieber-Emmons
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4130537?pdf=render