Candida albicans Shed Msb2 and Host Mucins Affect the Candidacidal Activity of Salivary Hst 5

Salivary Histatin 5 (Hst 5) is an antimicrobial peptide that exhibits potent antifungal activity towards Candida albicans, the causative agent of oral candidiasis. However, it exhibits limited activity in vivo, largely due to inactivation by salivary components of both host and pathogen origin. Prot...

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Bibliographic Details
Main Authors: Sumant Puri, Justin Friedman, Darpan Saraswat, Rohitashw Kumar, Rui Li, Donna Ruszaj, Mira Edgerton
Format: Article
Language:English
Published: MDPI AG 2015-10-01
Series:Pathogens
Subjects:
Online Access:http://www.mdpi.com/2076-0817/4/4/752