Induction of Micronuclei in Cervical Cancer Treated with Radiotherapy

Induction of Micronuclei in Cervical Cancer Treated with Radiotherapy

Micronuclei (MN) trigger antitumor immune responses via the cyclic GMP-AMP synthase-signaling effector stimulator of interferon genes (cGAS-STING) pathway. Radiotherapy induces MN in peripheral blood lymphocytes. However, data for solid tumors are lacking. Here, we analyzed MN post-radiotherapy in s...

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Bibliographic Details
Main Authors: Daijiro Kobayashi, Takahiro Oike, Kazutoshi Murata, Daisuke Irie, Yuka Hirota, Hiro Sato, Atsushi Shibata, Tatsuya Ohno
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Journal of Personalized Medicine
Subjects:
micronuclei
uterine cervical cancer
radiotherapy
cGAS
STING
abscopal effect
Online Access:https://www.mdpi.com/2075-4426/10/3/110

Internet

https://www.mdpi.com/2075-4426/10/3/110

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