A protein prioritization approach tailored for the FA/BRCA pathway.

A protein prioritization approach tailored for the FA/BRCA pathway.

Fanconi anemia (FA) is a heterogeneous recessive disorder associated with a markedly elevated risk to develop cancer. To date sixteen FA genes have been identified, three of which predispose heterozygous mutation carriers to breast cancer. The FA proteins work together in a genome maintenance pathwa...

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Bibliographic Details
Main Authors: Anneke Haitjema, Bernd W Brandt, Najim Ameziane, Patrick May, Jaap Heringa, Johan P de Winter, Hans Joenje, Josephine C Dorsman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3631253?pdf=render

Internet

http://europepmc.org/articles/PMC3631253?pdf=render

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