Chronic Binge Alcohol Administration Dysregulates Hippocampal Genes Involved in Immunity and Neurogenesis in Simian Immunodeficiency Virus-Infected Macaques

Chronic Binge Alcohol Administration Dysregulates Hippocampal Genes Involved in Immunity and Neurogenesis in Simian Immunodeficiency Virus-Infected Macaques

Alcohol use disorders (AUD) exacerbate neurocognitive dysfunction in Human Immunodeficiency Virus (HIV+) patients. We have shown that chronic binge alcohol (CBA) administration (13–14 g EtOH/kg/wk) prior to and during simian immunodeficiency virus (SIV) infection in rhesus macaques unmasks learning...

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Bibliographic Details
Main Authors: John K. Maxi, Matt Dean, Jovanny Zabaleta, Krzysztof Reiss, Gregory J. Bagby, Steve Nelson, Peter J. Winsauer, Francesca Peruzzi, Patricia E. Molina
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:Biomolecules
Subjects:
SIV
alcohol
macaque
hippocampus
neural progenitor cells
Tat
microarray
neuroinflammation
neurogenesis
Online Access:http://www.mdpi.com/2218-273X/6/4/43

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http://www.mdpi.com/2218-273X/6/4/43

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