Lipopolyplex for therapeutic gene delivery and its application for the treatment of Parkinson’s disease

Abstract: Lipopolyplex is a core-shell structure composed of nucleic acid, polycation and lipid. As a non-viral gene delivery vector, lipopolyplex combining the advantages of polyplex and lipoplex has shown superior colloidal stability, reduced cytotoxicity, extremely high gene transfection efficien...

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Bibliographic Details
Main Authors: Wei eChen, Hui eLi, Zhenguo eLiu, Weien eYuan
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-04-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2016.00068/full