Validation of next generation sequencing technologies in comparison to current diagnostic gold standards for BRAF, EGFR and KRAS mutational analysis.

Validation of next generation sequencing technologies in comparison to current diagnostic gold standards for BRAF, EGFR and KRAS mutational analysis.

Next Generation Sequencing (NGS) has the potential of becoming an important tool in clinical diagnosis and therapeutic decision-making in oncology owing to its enhanced sensitivity in DNA mutation detection, fast-turnaround of samples in comparison to current gold standard methods and the potential...

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Bibliographic Details
Main Authors: Clare M McCourt, Darragh G McArt, Ken Mills, Mark A Catherwood, Perry Maxwell, David J Waugh, Peter Hamilton, Joe M O'Sullivan, Manuel Salto-Tellez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3724913?pdf=render

Internet

http://europepmc.org/articles/PMC3724913?pdf=render

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