G-Quadruplex Binders Induce Immunogenic Cell Death Markers in Aggressive Breast Cancer Cells

Background: DNA G-quadruplex (G4) structures represent potential anti-cancer targets. In this study, we compared the effect of two G4-targeting compounds, C066-3108 and the gold standard BRACO-19. Methods: In breast and prostate cancer cells, cytotoxicity induced by both molecules was measured by a...

Full description

Bibliographic Details
Main Authors: Sarah Di Somma, Jussara Amato, Nunzia Iaccarino, Bruno Pagano, Antonio Randazzo, Giuseppe Portella, Anna Maria Malfitano
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/11/11/1797