Altered cellular infiltration and cytokine levels during early <it>Mycobacterium tuberculosis </it><it>sigC </it>mutant infection are associated with late-stage disease attenuation and milder immunopathology in mice

<p>Abstract</p> <p>Background</p> <p>Mouse virulence assessments of certain <it>Mycobacterium tuberculosis </it>mutants have revealed an immunopathology defect in which high tissue CFU counts are observed but the tissue pathology and lethality are reduced. &...

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Bibliographic Details
Main Authors: McMurray David N, Geiman Deborah E, Converse Paul J, Ly Lan H, Abdul-Majid Khairul-Bariah, Bishai William R
Format: Article
Language:English
Published: BMC 2008-09-01
Series:BMC Microbiology
Online Access:http://www.biomedcentral.com/1471-2180/8/151