Altered cellular infiltration and cytokine levels during early <it>Mycobacterium tuberculosis </it><it>sigC </it>mutant infection are associated with late-stage disease attenuation and milder immunopathology in mice
<p>Abstract</p> <p>Background</p> <p>Mouse virulence assessments of certain <it>Mycobacterium tuberculosis </it>mutants have revealed an immunopathology defect in which high tissue CFU counts are observed but the tissue pathology and lethality are reduced. &...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2008-09-01
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Series: | BMC Microbiology |
Online Access: | http://www.biomedcentral.com/1471-2180/8/151 |