Renal Expression of Light Chain Binding Proteins

Renal Expression of Light Chain Binding Proteins

Overproduction of human light chains (LCs) and immunoglobulins can result in various forms of renal disease such as cast nephropathy, monoclonal immunoglobulin deposition disease, LC proximal tubulopathy, AL amyloidosis, and crystal storing histiocytosis. This is caused by cellular uptake of LCs and...

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Bibliographic Details
Main Authors: Thomas Reiter, Sahra Pajenda, David O'Connell, Ciara Lynch, Sebastian Kapps, Hermine Agis, Alice Schmidt, Ludwig Wagner, Nelson Leung, Wolfgang Winnicki
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Medicine
Subjects:
amyloidosis
multiple myeloma
light chains
light chain associated kidney disorders
monoclonal gammopathy
protein micro array analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2020.609582/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2020.609582/full

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