Dendritic cell-associated MAVS is required to control West Nile virus replication and ensuing humoral immune responses.

Dendritic cell-associated MAVS is required to control West Nile virus replication and ensuing humoral immune responses.

Mitochondrial antiviral signaling protein (MAVS) is a critical innate immune signaling protein that directs the actions of the RIG-I-like receptor (RLR) signaling pathway of RNA virus recognition and initiation of anti-viral immunity against West Nile virus (WNV). In the absence of MAVS, mice die mo...

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Bibliographic Details
Main Authors: Kelsey Roe, Daniela Giordano, Lucy B Young, Kevin E Draves, Ursula Holder, Mehul S Suthar, Michael Gale, Edward A Clark
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0218928

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https://doi.org/10.1371/journal.pone.0218928

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