The prolyl isomerase Pin1 modulates development of CD8+ cDC in mice.

Pin1 has previously been described to regulate cells that participate in both innate and adaptive immunity. Thus far, however, no role for Pin1 has been described in modulating conventional dendritic cells, innate antigen presenting cells that potently activate naïve T cells, thereby bridging innate...

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Bibliographic Details
Main Authors: Theresa J Barberi, Alexis Dunkle, You-Wen He, Luigi Racioppi, Anthony R Means
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3251613?pdf=render