Adenylylation of Gyrase and Topo IV by FicT Toxins Disrupts Bacterial DNA Topology

Adenylylation of Gyrase and Topo IV by FicT Toxins Disrupts Bacterial DNA Topology

Toxin-antitoxin (TA) modules are ubiquitous molecular switches controlling bacterial growth via the release of toxins that inhibit cell proliferation. Most of these toxins interfere with protein translation, but a growing variety of other mechanisms hints at a diversity that is not yet fully appreci...

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Bibliographic Details
Main Authors: Alexander Harms, Frédéric Valentin Stanger, Patrick Daniel Scheu, Imke Greet de Jong, Arnaud Goepfert, Timo Glatter, Kenn Gerdes, Tilman Schirmer, Christoph Dehio
Format: Article
Language:English
Published: Elsevier 2015-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715008463

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http://www.sciencedirect.com/science/article/pii/S2211124715008463

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