Var2CSA minimal CSA binding region is located within the N-terminal region.

Var2CSA, a key molecule linked with pregnancy-associated malaria (PAM), causes sequestration of Plasmodium falciparum infected erythrocytes (PEs) in the placenta by adhesion to chondroitin sulfate A (CSA). Var2CSA possesses a 300 kDa extracellular region composed of six Duffy-binding like (DBL) doma...

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Bibliographic Details
Main Authors: Anand Srivastava, Stéphane Gangnard, Sébastien Dechavanne, Farroudja Amirat, Anita Lewit Bentley, Graham A Bentley, Benoît Gamain
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21625526/?tool=EBI