A Computational, Tissue-Realistic Model of Pressure Ulcer Formation in Individuals with Spinal Cord Injury.

People with spinal cord injury (SCI) are predisposed to pressure ulcers (PU). PU remain a significant burden in cost of care and quality of life despite improved mechanistic understanding and advanced interventions. An agent-based model (ABM) of ischemia/reperfusion-induced inflammation and PU (the...

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Bibliographic Details
Main Authors: Cordelia Ziraldo, Alexey Solovyev, Ana Allegretti, Shilpa Krishnan, M Kristi Henzel, Gwendolyn A Sowa, David Brienza, Gary An, Qi Mi, Yoram Vodovotz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-06-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4482429?pdf=render