Transcriptomic analysis associated with reversal of cisplatin sensitivity in drug resistant osteosarcoma cells after a drug holiday

Transcriptomic analysis associated with reversal of cisplatin sensitivity in drug resistant osteosarcoma cells after a drug holiday

Abstract Background Resistance to chemotherapy is one of the major hurdles in current cancer therapy. With the increasing occurrence of drug resistance, a paradigm shift in treatment strategy is required. Recently “medication vacation” has emerged as a unique, yet uncomplicated strategy in which wit...

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Bibliographic Details
Main Authors: Divya Niveditha, Harshita Sharma, Syamantak Majumder, Sudeshna Mukherjee, Rajdeep Chowdhury, Shibasish Chowdhury
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Cancer
Subjects:
Osteosarcoma
RNA-sequencing
Drug-resistance
Drug-holiday
Online Access:http://link.springer.com/article/10.1186/s12885-019-6300-2

Internet

http://link.springer.com/article/10.1186/s12885-019-6300-2

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