mTORC1 Prevents Epithelial Damage During Inflammation and Inhibits Colitis-Associated Colorectal Cancer Development

Epithelial cells lining the intestinal mucosa constitute a selective-semipermeable barrier acting as first line of defense in the organism. The number of those cells remains constant during physiological conditions, but disruption of epithelial cell homeostasis has been observed in several pathologi...

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Bibliographic Details
Main Authors: I.Z. Gutiérrez-Martínez, J.F. Rubio, Z.L. Piedra-Quintero, O. Lopez-Mendez, C. Serrano, E. Reyes-Maldonado, C. Salinas-Lara, A. Betanzos, M. Shibayama, A. Silva-Olivares, A. Candelario-Martinez, M.A. Meraz-Ríos, M. Schnoor, N. Villegas-Sepúlveda, P. Nava
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523318303310