Structure and compositional analysis of aluminum oxyhydroxide adsorbed pertussis vaccine
Purpose: The goal of this study was to characterize an acellular pertussis vaccine (Tdap) containing genetically modified pertussis toxin (gdPT) and TLR agonist adsorbed to AlOOH adjuvant. Methods: Several analytical tools including nanoDSF, FTIR, and LD were used to examine the conformation of nove...
Main Authors: | Jessica Duprez, Kristen Kalbfleisch, Sasmit Deshmukh, Jessie Payne, Manjit Haer, Wayne Williams, Ibrahim Durowoju, Marina Kirkitadze |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-01-01
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Series: | Computational and Structural Biotechnology Journal |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2001037020305481 |
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