Structural Analysis of Variability and Interaction of the N-terminal of the Oncogenic Effector CagA of Helicobacter pylori with Phosphatidylserine

Structural Analysis of Variability and Interaction of the N-terminal of the Oncogenic Effector CagA of Helicobacter pylori with Phosphatidylserine

Helicobacter pylori cytotoxin-associated gene A protein (CagA) has been associated with the increase in virulence and risk of cancer. It has been demonstrated that CagA’s translocation is dependent on its interaction with phosphatidylserine. We evaluated the variability of the N-terminal C...

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Bibliographic Details
Main Authors: Cindy P. Ulloa-Guerrero, Maria del Pilar Delgado, Carlos A. Jaramillo
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:International Journal of Molecular Sciences
Subjects:
CagA
phosphatidylserine
phosphatidylserine mutations
conservation N-terminal CagA
homology modeling
molecular docking
Online Access:http://www.mdpi.com/1422-0067/19/10/3273

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http://www.mdpi.com/1422-0067/19/10/3273

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