Urinary expression of let-7c cluster as non-invasive tool to assess the risk of disease progression in patients with high grade non-muscle invasive bladder Cancer: a pilot study

Urinary expression of let-7c cluster as non-invasive tool to assess the risk of disease progression in patients with high grade non-muscle invasive bladder Cancer: a pilot study

Abstract Background High grade non-muscle-invasive bladder cancer (HG-NMIBC) is a heterogeneous disease with variable risk of progression. Urinary microRNAs are promising biomarkers for BC detection and surveillance. Let-7c-5p miRNA, clustered with miR-99a-5p and -125b-5p, is deregulated in cancer,...

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Bibliographic Details
Main Authors: Manuela Spagnuolo, Manuela Costantini, Mariaconsiglia Ferriero, Marco Varmi, Isabella Sperduti, Giulia Regazzo, Lucia Cicchillitti, Ana Belén Díaz Méndez, Giovanni Cigliana, Vincenzo Pompeo, Andrea Russo, Valentina Laquintana, Riccardo Mastroianni, Giulia Piaggio, Umberto Anceschi, Aldo Brassetti, Alfredo Bove, Gabriele Tuderti, Rocco Simone Flammia, Michele Gallucci, Giuseppe Simone, Maria Giulia Rizzo
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Non-muscle-invasive bladder cancer
microRNA
Let-7c cluster, urinary biomarkers, progression free survival
Online Access:http://link.springer.com/article/10.1186/s13046-020-01550-w

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http://link.springer.com/article/10.1186/s13046-020-01550-w

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