Heat Shock Protein 90 Triggers Multi-Drug Resistance of Ovarian Cancer via AKT/GSK3β/β-Catenin Signaling

Heat Shock Protein 90 Triggers Multi-Drug Resistance of Ovarian Cancer via AKT/GSK3β/β-Catenin Signaling

Ovarian cancer is the most lethal gynaecologic tumor, with which multi-drug resistance as the major therapeutic hindrance. Heat shock protein 90 (Hsp90) has been involved in cancer malignant behaviors. However, its role and mechanism in multi-drug resistance of ovarian cancer remains poorly understo...

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Bibliographic Details
Main Authors: Lan Yin, Yuhan Yang, Wanglong Zhu, Yu Xian, Zhengyu Han, Houyi Huang, Liaotian Peng, Kun Zhang, Ye Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Oncology
Subjects:
multi-drug resistance
heat shock protein 90
ovarian cancer
β-catenin
chemotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.620907/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.620907/full

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