TBX2-positive cells represent a multi-potent mesenchymal progenitor pool in the developing lung

TBX2-positive cells represent a multi-potent mesenchymal progenitor pool in the developing lung

Abstract Background In the embryonic mammalian lung, mesenchymal cells act both as a signaling center for epithelial proliferation, differentiation and morphogenesis as well as a source for a multitude of differentiated cell types that support the structure of the developing and mature organ. Whethe...

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Bibliographic Details
Main Authors: Irina Wojahn, Timo H. Lüdtke, Vincent M. Christoffels, Mark-Oliver Trowe, Andreas Kispert
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Respiratory Research
Subjects:
Tbx2
Lineage tracing
Pulmonary mesenchyme
Smooth muscle cells
Lung development
Online Access:https://doi.org/10.1186/s12931-019-1264-y

Internet

https://doi.org/10.1186/s12931-019-1264-y

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