Design and Synthesis of Novel 1,3-Thiazole and 2-Hydrazinyl-1,3-Thiazole Derivatives as Anti-<i>Candida</i> Agents: In Vitro Antifungal Screening, Molecular Docking Study, and Spectroscopic Investigation of their Binding Interaction with Bovine Serum Albumin

In the context of there being a limited number of clinically approved drugs for the treatment of <i>Candida</i> sp.-based infections, along with the rapid development of resistance to the existing antifungals, two novel series of 4-phenyl-1,3-thiazole and 2-hydrazinyl-4-phenyl-1,3-thiazo...

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Bibliographic Details
Main Authors: Andreea-Iulia Pricopie, Ioana Ionuț, Gabriel Marc, Anca-Maria Arseniu, Laurian Vlase, Adriana Grozav, Luiza Ioana Găină, Dan C. Vodnar, Adrian Pîrnău, Brîndușa Tiperciuc, Ovidiu Oniga
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/24/19/3435