Standardization of T1w/T2w Ratio Improves Detection of Tissue Damage in Multiple Sclerosis

Standardization of T1w/T2w Ratio Improves Detection of Tissue Damage in Multiple Sclerosis

Normal appearing white matter (NAWM) damage develops early in multiple sclerosis (MS) and continues in the absence of new lesions. The ratio of T1w and T2w (T1w/T2w ratio), a measure of white matter integrity, has previously shown reduced intensity values in MS NAWM. We evaluate the validity of a st...

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Bibliographic Details
Main Authors: Graham Cooper, Carsten Finke, Claudia Chien, Alexander U. Brandt, Susanna Asseyer, Klemens Ruprecht, Judith Bellmann-Strobl, Friedemann Paul, Michael Scheel
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Neurology
Subjects:
magnetic resonance imaging techniques
multiple sclerosis
normal appearing white matter
T1w/T2w ratio
relapsing-remitting
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.00334/full

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https://www.frontiersin.org/article/10.3389/fneur.2019.00334/full

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