Knee degenerative osteoarthritis secondary to ochronosis (case report)
Alkaptonuria is rare disease with deficiency of homogentisate-1,2-dioxygenase enzyme, resulting in excess deposition of homogentisic acid in connective tissue. This deposition leads to ochronosis - brownish-black pigmentation of connective tissue. The result of pigmentation is weakness of connective...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Vreden Russian Research Institute of Traumatology and Orthopedics
2013-06-01
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| Series: | Travmatologiâ i Ortopediâ Rossii |
| Subjects: | |
| Online Access: | https://journal.rniito.org/jour/article/view/340 |