FOXP3 expression is upregulated in CD4T cells in progressive HIV-1 infection and is a marker of disease severity.

FOXP3 expression is upregulated in CD4T cells in progressive HIV-1 infection and is a marker of disease severity.

Understanding the role of different classes of T cells during HIV infection is critical to determining which responses correlate with protective immunity. To date, it is unclear whether alterations in regulatory T cell (Treg) function are contributory to progression of HIV infection.FOXP3 expression...

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Bibliographic Details
Main Authors: Melinda S Suchard, Elizabeth Mayne, Victoria A Green, Sharon Shalekoff, Samantha L Donninger, Wendy S Stevens, Clive M Gray, Caroline T Tiemessen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2909259?pdf=render

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http://europepmc.org/articles/PMC2909259?pdf=render

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