Reductions in Myeloid-Derived Suppressor Cells and Lung Metastases using AZD4547 Treatment of a Metastatic Murine Breast Tumor Model
Background: AZD4547, a small-molecule inhibitor targeting the tyrosine kinase of Fibroblast Growth Factor Receptors (FGFRs), is currently under phase II clinical study for human subjects having breast cancer, while the underlying mechanism remains elusive. The aim of this study is to explore the pot...
Main Authors: | Li Liu, Ting Hong Ye, Yuan Ping Han, Hang Song, Yong Kui Zhang, Yong Xia, Ning Yu Wang, Ying Xiong, Xue Jiao Song, Yong Xia Zhu, De Liang Li, Jun Zeng, Kai Ran, Cui Ting Peng, Yu Quan Wei, Luo Ting Yu |
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Format: | Article |
Language: | English |
Published: |
Cell Physiol Biochem Press GmbH & Co KG
2014-03-01
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Series: | Cellular Physiology and Biochemistry |
Subjects: | |
Online Access: | http://www.karger.com/Article/FullText/358640 |
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