The Tumorigenic Effect of Sphingosine Kinase 1 and Its Potential Therapeutic Target

The Tumorigenic Effect of Sphingosine Kinase 1 and Its Potential Therapeutic Target

Sphingosine kinase 1 (SPHK1) regulates cell proliferation and survival by converting sphingosine to the signaling mediator sphingosine 1-phosphate (S1P). SPHK1 is widely overexpressed in most cancers, promoting tumor progression and is associated with clinical prognosis. Numerous studies have explor...

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Bibliographic Details
Main Authors: Xianwang Wang PhD, Yong Sun MM, Xiaochun Peng PhD, Syed Manzar Abbas Shah Naqvi MB, Yue Yang MB, Jing Zhang MM, Meiwen Chen MB, Yuan Chen MB, Hongyue Chen MB, Huizi Yan MB, Guangliang Wei MB, Peng Hong PhD, Yingying Lu PhD
Format: Article
Language:English
Published: SAGE Publishing 2020-12-01
Series:Cancer Control
Online Access:https://doi.org/10.1177/1073274820976664

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https://doi.org/10.1177/1073274820976664

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