Selection and characterization of single-stranded DNA aptamers against interleukin-5

Asthma as a chronic inflammatory disorder is associated with many cytokines like interleukin-5 (IL-5) which plays essential role in eosinophil differentiation and maturation. Accordingly, blockage of IL-5 using mepalizumab has been considered as a promising therapeutic approach for asthma. Despite t...

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Bibliographic Details
Main Authors: Mina Jamalvandi, Hossein Khanahmad, Shiva Irani, Sayad Bastaminezhad
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Research in Pharmaceutical Sciences
Subjects:
Online Access:http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2019;volume=14;issue=6;spage=515;epage=523;aulast=Jamalvandi