Analysis of the Microprocessor in Dictyostelium: The Role of RbdB, a dsRNA Binding Protein.

Analysis of the Microprocessor in Dictyostelium: The Role of RbdB, a dsRNA Binding Protein.

We identified the dsRNA binding protein RbdB as an essential component in miRNA processing in Dictyostelium discoideum. RbdB is a nuclear protein that accumulates, together with Dicer B, in nucleolar foci reminiscent of plant dicing bodies. Disruption of rbdB results in loss of miRNAs and accumulati...

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Bibliographic Details
Main Authors: Doreen Meier, Janis Kruse, Jann Buttlar, Michael Friedrich, Fides Zenk, Benjamin Boesler, Konrad U Förstner, Christian Hammann, Wolfgang Nellen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-06-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4894637?pdf=render

Internet

http://europepmc.org/articles/PMC4894637?pdf=render

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