Mitotic Kinases and p53 Signaling

Mitosis is tightly regulated and any errors in this process often lead to aneuploidy, genomic instability, and tumorigenesis. Deregulation of mitotic kinases is significantly associated with improper cell division and aneuploidy. Because of their importance during mitosis and the relevance to ca...

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Bibliographic Details
Main Authors: Geun-Hyoung Ha, Eun-Kyoung Yim Breuer
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Biochemistry Research International
Online Access:http://dx.doi.org/10.1155/2012/195903